Persistent Dystrophin Protein Restoration 90 Days after a Course of Intraperitoneally Administered Naked 2′OMePS AON and ZM2 NP-AON Complexes in mdx Mice

In Duchenne muscular dystrophy, the exon-skipping approach has obtained proof of concept in animal models, myogenic cell cultures, and following local and systemic administration in Duchenne patients. Indeed, we have previously demonstrated that low doses (7.5 mg/Kg/week) of 2′-O-methyl-phosphorothi...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Bassi, Elena, Falzarano, Sofia, Fabris, Marina, Gualandi, Francesca, Merlini, Luciano, Vattemi, Gaetano, Perrone, Daniela, Marchesi, Elena, Sabatelli, Patrizia, Sparnacci, Katia, Laus, Michele, Bonaldo, Paolo, Rimessi, Paola, Braghetta, Paola, Ferlini, Alessandra
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Hindawi Publishing Corporation 2012
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3471065/
https://ncbi.nlm.nih.gov/pubmed/23091362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/897076
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