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The GLI1 Splice Variant TGLI1 Promotes Glioblastoma Angiogenesis and Growth

We investigated truncated glioma-associated oncogene homolog 1 (TGLI1) that behaves as gain-of-function GLI1 and promotes tumor cell migration and invasion. Herein, we report that TGLI1 had a higher propensity than GLI1 to enhance glioblastoma angiogenesis and growth, both in vivo and in vitro. TGLI...

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Autores principales: Zhu, Hu, Carpenter, Richard L., Han, Woody, Lo, Hui-Wen
Formato: Artigo
Lenguaje:Inglês
Publicado: 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3874262/
https://ncbi.nlm.nih.gov/pubmed/24045042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2013.09.014
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