The gain-of-function GLI1 transcription factor TGLI1 enhances expression of VEGF-C and TEM7 to promote glioblastoma angiogenesis

We recently discovered that truncated glioma-associated oncogene homolog 1 (TGLI1) is highly expressed in glioblastoma (GBM) and linked to increased GBM vascularity. The mechanisms underlying TGLI1-mediated angiogenesis are unclear. In this study, we compared TGLI1- with GLI1-expressing GBM xenograf...

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Publicat a:Oncotarget
Autors principals: Carpenter, Richard L., Paw, Ivy, Zhu, Hu, Sirkisoon, Sherona, Xing, Fei, Watabe, Kounosuke, Debinski, Waldemar, Lo, Hui-Wen
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2015
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4673189/
https://ncbi.nlm.nih.gov/pubmed/26093087
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