The dynamics of genome replication using deep sequencing

Eukaryotic genomes are replicated from multiple DNA replication origins. We present complementary deep sequencing approaches to measure origin location and activity in Saccharomyces cerevisiae. Measuring the increase in DNA copy number during a synchronous S-phase allowed the precise determination o...

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Autors principals: Müller, Carolin A., Hawkins, Michelle, Retkute, Renata, Malla, Sunir, Wilson, Ray, Blythe, Martin J., Nakato, Ryuichiro, Komata, Makiko, Shirahige, Katsuhiko, de Moura, Alessandro P.S., Nieduszynski, Conrad A.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2014
Matèries:
Methods Online
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3874191/
https://ncbi.nlm.nih.gov/pubmed/24089142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt878
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