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Accelerated growth in the absence of DNA replication origins

DNA replication initiates at defined sites called origins, which serve as binding sites for initiator proteins that recruit the replicative machinery. Origins differ in number and structure across the three domains of life(1) and their properties determine the dynamics of chromosome replication. Bac...

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Detalhes bibliográficos
Main Authors: Hawkins, Michelle, Malla, Sunir, Blythe, Martin J., Nieduszynski, Conrad A., Allers, Thorsten
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3843117/
https://ncbi.nlm.nih.gov/pubmed/24185008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature12650
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