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Novel fluorescent genome editing reporters for monitoring DNA repair pathway utilization at endonuclease-induced breaks
The creation of a DNA break at a specific locus by a designer endonuclease can be harnessed to edit a genome. However, DNA breaks may engage one of several competing repair pathways that lead to distinct types of genomic alterations. Therefore, understanding the contribution of different repair path...
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| Principais autores: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3874187/ https://ncbi.nlm.nih.gov/pubmed/24121685 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt872 |
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