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A role for heterodimerization of μ and δ opiate receptors in enhancing morphine analgesia

Opiates such as morphine are the choice analgesic in the treatment of chronic pain. However their long-term use is limited because of the development of tolerance and dependence. Due to its importance in therapy, different strategies have been considered for making opiates such as morphine more effe...

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Bibliografske podrobnosti
izdano v:Proc Natl Acad Sci U S A
Principais autores: Gomes, Ivone, Gupta, Achla, Filipovska, Julija, Szeto, Hazel H., Pintar, John E., Devi, Lakshmi A.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2004
Teme:
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC387386/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15044695/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0307601101
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