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A role for heterodimerization of μ and δ opiate receptors in enhancing morphine analgesia

Opiates such as morphine are the choice analgesic in the treatment of chronic pain. However their long-term use is limited because of the development of tolerance and dependence. Due to its importance in therapy, different strategies have been considered for making opiates such as morphine more effe...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Gomes, Ivone, Gupta, Achla, Filipovska, Julija, Szeto, Hazel H., Pintar, John E., Devi, Lakshmi A.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2004
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Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC387386/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15044695/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0307601101
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