VMAT2 knockout mice: Heterozygotes display reduced amphetamine-conditioned reward, enhanced amphetamine locomotion, and enhanced MPTP toxicity

The brain vesicular monoamine transporter (VMAT2) pumps monoamine neurotransmitters and Parkinsonism-inducing dopamine neurotoxins such as 1-methyl-4-phenyl-phenypyridinium (MPP(+)) from neuronal cytoplasm into synaptic vesicles, from which amphetamines cause their release. Amphetamines and MPP(+) e...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Takahashi, Nobuyuki, Miner, Lucinda L., Sora, Ichiro, Ujike, Hiroshi, Revay, Randal S., Kostic, Vladimir, Jackson-Lewis, Vernice, Przedborski, Serge, Uhl, George R.
Formato: Artigo
Lenguaje:Inglês
Publicado: The National Academy of Sciences of the USA 1997
Materias:
Biological Sciences
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC23302/
https://ncbi.nlm.nih.gov/pubmed/9275230
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares