VMAT2 knockout mice: Heterozygotes display reduced amphetamine-conditioned reward, enhanced amphetamine locomotion, and enhanced MPTP toxicity

The brain vesicular monoamine transporter (VMAT2) pumps monoamine neurotransmitters and Parkinsonism-inducing dopamine neurotoxins such as 1-methyl-4-phenyl-phenypyridinium (MPP(+)) from neuronal cytoplasm into synaptic vesicles, from which amphetamines cause their release. Amphetamines and MPP(+) e...

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Podrobná bibliografie

Vydáno v:	Proc Natl Acad Sci U S A
Hlavní autoři:	Takahashi, Nobuyuki, Miner, Lucinda L., Sora, Ichiro, Ujike, Hiroshi, Revay, Randal S., Kostic, Vladimir, Jackson-Lewis, Vernice, Przedborski, Serge, Uhl, George R.
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	National Academy of Sciences 1997
Témata:	Biological Sciences
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC23302/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9275230/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.18.9938
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