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Rapid downregulation of NCX and PMCA in hippocampal neurons following H(2)O(2) oxidative stress

Na(+)/Ca(2+) exchangers (NCXs) and plasma membrane Ca(2+) pumps (PMCAs) are crucial for intracellular Ca(2+) homeostasis and Ca(2+) signaling. Elevated [Ca(2+)](i) is a hallmark of neurodegenerative disease and stroke. Here we studied the short-term effect of oxidative stress on the plasma membrane...

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Hlavní autoři: Kip, Sertac N., Strehler, Emanuel E.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2007
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3873835/
https://ncbi.nlm.nih.gov/pubmed/17446483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1196/annals.1387.005
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