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Rapid downregulation of NCX and PMCA in hippocampal neurons following H(2)O(2) oxidative stress
Na(+)/Ca(2+) exchangers (NCXs) and plasma membrane Ca(2+) pumps (PMCAs) are crucial for intracellular Ca(2+) homeostasis and Ca(2+) signaling. Elevated [Ca(2+)](i) is a hallmark of neurodegenerative disease and stroke. Here we studied the short-term effect of oxidative stress on the plasma membrane...
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| Главные авторы: | , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2007
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3873835/ https://ncbi.nlm.nih.gov/pubmed/17446483 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1196/annals.1387.005 |
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