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Hippocampal Neuronal Nitric Oxide Synthase Mediates the Stress-Related Depressive Behaviors of Glucocorticoids by Downregulating Glucocorticoid Receptor

The molecular mechanisms underlying the behavioral effects of glucocorticoids are poorly understood. We report here that hippocampal neuronal nitric oxide synthase (nNOS) is a crucial mediator. Chronic mild stress and glucocorticoids exposures caused hippocampal nNOS overexpression via activating mi...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Zhou, Qi-Gang, Zhu, Li-Juan, Chen, Chen, Wu, Hai-Yin, Luo, Chun-Xia, Chang, Lei, Zhu, Dong-Ya
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6633122/
https://ncbi.nlm.nih.gov/pubmed/21613472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0004-11.2011
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