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Mitochondrially targeted wild-type p53 induces apoptosis in a solid human tumor xenograft model

Classic but also novel roles of p53 are becoming increasingly well characterized. We previously showed that ex vivo retroviral transfer of mitochondrially targeted wild type p53 (mitop53) in the Eμ-myc mouse lymphoma model efficiently induces tumor cell killing in vivo. In an effort to further explo...

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Detalles Bibliográficos
Autores principales: Palacios, Gustavo, Crawford, Howard C., Vaseva, Angelina, Moll, Ute M.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2008
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3873818/
https://ncbi.nlm.nih.gov/pubmed/18719383
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