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Negative Inotropic Effects of High Mobility Box Group 1 Protein in Isolated Contracting Cardiac Myocytes

HMGB1 released from necrotic cells or macrophages functions as a late inflammatory mediator, and has been shown to induce cardiovascular collapse during sepsis. Thus far, however, the effect(s) of HMGB1 in the heart are not known. We determined the effects of HMGB1 on isolated feline cardiac myocyte...

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Hlavní autoři: Tzeng, Huei-Ping, Fan, Jinping, Vallejo, Jesus G., Dong, Jian Wen, Chen, Xiongwen, Houser, Steven R., Mann, Douglas L.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3873738/
https://ncbi.nlm.nih.gov/pubmed/18223193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00910.2007
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