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Amyloid Structures from Alzheimer’s Disease Patients

Lu and colleagues report the structures of β-amyloid fibrils seeded from the brain extracts of two Alzheimer’s disease patients, a game-changing study that could open new avenues for structure-based design of diagnostic imaging agents and aggregation inhibiting drugs.

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Bibliographic Details
Main Author: Rienstra, Chad M.
Format: Artigo
Language:Inglês
Published: 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3873726/
https://ncbi.nlm.nih.gov/pubmed/24119671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2013.09.010
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