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Common Polymorphisms in Human Langerin Change Specificity for Glycan Ligands
Langerin, a C-type lectin on Langerhans cells, mediates carbohydrate-dependent uptake of pathogens in the first step of antigen presentation to the adaptive immune system. Langerin binds a diverse range of carbohydrates including high mannose structures, fucosylated blood group antigens, and glycans...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Biochemistry and Molecular Biology
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3873535/ https://ncbi.nlm.nih.gov/pubmed/24217250 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.528000 |
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