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Distinct transcriptional programs in thymocytes responding to T cell receptor, Notch, and positive selection signals

T cell antigen receptor (TCR) signaling is necessary but not sufficient to promote the positive selection of CD4(+)CD8(+) thymocytes into CD4(+) or CD8(+) mature T cells. Notch signaling has also been implicated as a potential regulator of both CD4/CD8 T cell development and TCR signaling. However,...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Huang, Yina H., Li, Dongling, Winoto, Astar, Robey, Ellen A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2004
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC387352/
https://ncbi.nlm.nih.gov/pubmed/15044701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0401133101
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