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Distinct transcriptional programs in thymocytes responding to T cell receptor, Notch, and positive selection signals
T cell antigen receptor (TCR) signaling is necessary but not sufficient to promote the positive selection of CD4(+)CD8(+) thymocytes into CD4(+) or CD8(+) mature T cells. Notch signaling has also been implicated as a potential regulator of both CD4/CD8 T cell development and TCR signaling. However,...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2004
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC387352/ https://ncbi.nlm.nih.gov/pubmed/15044701 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0401133101 |
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