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A global suppressor motif for p53 cancer mutants
The transcription factor and tumor suppressor protein p53 is frequently inactivated in human cancers. In many cases, p53 gene mutations result in high levels of inactive, full-length p53 protein with one amino acid change in the core domain that recognizes p53 DNA-binding sites. The ability to endow...
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| Main Authors: | , , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
National Academy of Sciences
2004
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC387351/ https://ncbi.nlm.nih.gov/pubmed/15037740 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0401162101 |
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