Overexpression of LIM and SH3 Protein 1 Leading to Accelerated G2/M Phase Transition Contributes to Enhanced Tumourigenesis in Oral Cancer

BACKGROUND: LIM and SH3 protein 1 (LASP-1) is a specific focal adhesion protein involved in several malignant tumors. However, its role in oral squamous cell carcinoma (OSCC) is unknown. The aim of this study was to characterize the role and molecular status/mechanism of LASP-1 in OSCC. METHODS: We...

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Autores principales: Shimizu, Fumie, Shiiba, Masashi, Ogawara, Katsunori, Kimura, Ryota, Minakawa, Yasuyuki, Baba, Takao, Yokota, Satoshi, Nakashima, Dai, Higo, Morihiro, Kasamatsu, Atsushi, Sakamoto, Yosuke, Tanzawa, Hideki, Uzawa, Katsuhiro
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3873298/
https://ncbi.nlm.nih.gov/pubmed/24386158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0083187
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