Overexpression of LIM and SH3 Protein 1 Leading to Accelerated G2/M Phase Transition Contributes to Enhanced Tumourigenesis in Oral Cancer

BACKGROUND: LIM and SH3 protein 1 (LASP-1) is a specific focal adhesion protein involved in several malignant tumors. However, its role in oral squamous cell carcinoma (OSCC) is unknown. The aim of this study was to characterize the role and molecular status/mechanism of LASP-1 in OSCC. METHODS: We...

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Detalhes bibliográficos
Main Authors: Shimizu, Fumie, Shiiba, Masashi, Ogawara, Katsunori, Kimura, Ryota, Minakawa, Yasuyuki, Baba, Takao, Yokota, Satoshi, Nakashima, Dai, Higo, Morihiro, Kasamatsu, Atsushi, Sakamoto, Yosuke, Tanzawa, Hideki, Uzawa, Katsuhiro
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3873298/
https://ncbi.nlm.nih.gov/pubmed/24386158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0083187
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