Glutamate acid decarboxylase 1 promotes metastasis of human oral cancer by β-catenin translocation and MMP7 activation

BACKGROUND: Glutamate decarboxylase 1 (GAD1), a rate-limiting enzyme in the production of γ-aminobutyric acid (GABA), is found in the GABAergic neurons of the central nervous system. Little is known about the relevance of GAD1 to oral squamous cell carcinoma (OSCC). We investigated the expression st...

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Autores principales: Kimura, Ryota, Kasamatsu, Atsushi, Koyama, Tomoyoshi, Fukumoto, Chonji, Kouzu, Yukinao, Higo, Morihiro, Endo-Sakamoto, Yosuke, Ogawara, Katsunori, Shiiba, Masashi, Tanzawa, Hideki, Uzawa, Katsuhiro
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3866561/
https://ncbi.nlm.nih.gov/pubmed/24261884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-13-555
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