Lysophosphatidylcholine Acyltransferase1 Overexpression Promotes Oral Squamous Cell Carcinoma Progression via Enhanced Biosynthesis of Platelet-Activating Factor

BACKGROUND: The relevance of lysophosphatidylcholine acyltransferase1 (LPCAT1), a cytosolic enzyme in the remodeling pathway of phosphatidylcholine metabolism, in oral squamous cell carcinoma (OSCC) is unknown. We investigated LPCAT1 expression and its functional mechanism in OSCCs. METHODS: We anal...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Shida-Sakazume, Tomomi, Endo-Sakamoto, Yosuke, Unozawa, Motoharu, Fukumoto, Chonji, Shimada, Ken, Kasamatsu, Atsushi, Ogawara, Katsunori, Yokoe, Hidetaka, Shiiba, Masashi, Tanzawa, Hideki, Uzawa, Katsuhiro
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4372572/
https://ncbi.nlm.nih.gov/pubmed/25803864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0120143
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