Discovery and Preclinical Characterization of Novel Small Molecule TRK and ROS1 Tyrosine Kinase Inhibitors for the Treatment of Cancer and Inflammation

Receptor tyrosine kinases (RTKs), in response to their growth factor ligands, phosphorylate and activate downstream signals important for physiological development and pathological transformation. Increased expression, activating mutations and rearrangement fusions of RTKs lead to cancer, inflammati...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Narayanan, Ramesh, Yepuru, Muralimohan, Coss, Christopher C., Wu, Zhongzhi, Bauler, Matthew N., Barrett, Christina M., Mohler, Michael L., Wang, Yun, Kim, Juhyun, Snyder, Linda M., He, Yali, Levy, Nelson, Miller, Duane D., Dalton, James T.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2013
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3873281/
https://ncbi.nlm.nih.gov/pubmed/24386191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0083380
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia