Selective Androgen Receptor Modulators (SARMs) Negatively Regulate Triple-Negative Breast Cancer Growth and Epithelial:Mesenchymal Stem Cell Signaling

INTRODUCTION: The androgen receptor (AR) is the most highly expressed steroid receptor in breast cancer with 75–95% of estrogen receptor (ER)-positive and 40–70% of ER-negative breast cancers expressing AR. Though historically breast cancers were treated with steroidal androgens, their use fell from...

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Main Authors: Narayanan, Ramesh, Ahn, Sunjoo, Cheney, Misty D., Yepuru, Muralimohan, Miller, Duane D., Steiner, Mitchell S., Dalton, James T.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2014
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4114483/
https://ncbi.nlm.nih.gov/pubmed/25072326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0103202
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