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Arylisothiocyanato selective androgen receptor modulators (SARMs) for prostate cancer

A new series of androgen receptor targeted agents (ARTA) was prepared and tested in androgen-dependent and -independent prostate cancer cell lines. These agents were bicalutamide analogs with isothiocyanato substituted B-rings. Also, the linker sulfone of R-bicalutamide was maintained or replaced wi...

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Detalhes bibliográficos
Main Authors: Hwang, Dong Jin, Yang, Jun, Xu, Huiping, Rakov, Igor M., Mohler, Michael L., Dalton, James T., Miller, Duane D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2234576/
https://ncbi.nlm.nih.gov/pubmed/16828557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2006.06.019
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