Optimizing Melphalan Pharmacokinetics in Regional Melanoma Therapy: Does Correcting for Ideal Body Weight Alter Regional Response or Toxicity?

BACKGROUND: This study aims to determine what effect correcting melphalan dosing for ideal body weight (IBW) has on toxicity and response in isolated limb infusion (ILI) in patients with advanced extremity melanoma. METHODS: This was an open observational study examining whether correcting the melph...

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Hlavní autoři: McMahon, N., Cheng, T. Y., Beasley, G. M., Spasojevic, I., Petros, W., Augustine, C. K., Zipfel, P., Padussis, J. C., Sanders, G., Tyler, Douglas S.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3872993/
https://ncbi.nlm.nih.gov/pubmed/19184236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1245/s10434-008-0288-1
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