Načítá se...

TopBP1 recruits Brg1/Brm to repress E2F1-induced apoptosis, a novel pRb-independent and E2F1-specific control for cell survival

TopBP1 (DNA topoisomerase IIβ binding protein I) contains multiple BRCT domains and is involved in replication and the DNA damage checkpoint. Through its BRCT domain, TopBP1 interacts with and represses exclusively E2F1 but not other E2F factors. This regulation of E2F1 transcriptional activity is m...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Liu, Kang, Luo, Yuhong, Lin, Fang-Tsyr, Lin, Weei-Chin
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2004
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC387242/
https://ncbi.nlm.nih.gov/pubmed/15075294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1180204
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!