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A DNA Damage-Regulated BRCT-Containing Protein, TopBP1, Is Required for Cell Survival

BRCA1 carboxyl-terminal (BRCT) motifs are present in a number of proteins involved in DNA repair and/or DNA damage-signaling pathways. Human DNA topoisomerase II binding protein 1 (TopBP1) contains eight BRCT motifs and shares sequence similarity with the fission yeast Rad4/Cut5 protein and the budd...

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Detalhes bibliográficos
Main Authors: Yamane, Kazuhiko, Wu, Xianglin, Chen, Junjie
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC139754/
https://ncbi.nlm.nih.gov/pubmed/11756551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.2.555-566.2002
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