A DNA Damage-Regulated BRCT-Containing Protein, TopBP1, Is Required for Cell Survival

BRCA1 carboxyl-terminal (BRCT) motifs are present in a number of proteins involved in DNA repair and/or DNA damage-signaling pathways. Human DNA topoisomerase II binding protein 1 (TopBP1) contains eight BRCT motifs and shares sequence similarity with the fission yeast Rad4/Cut5 protein and the budd...

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Détails bibliographiques

Publié dans:	Mol Cell Biol
Auteurs principaux:	Yamane, Kazuhiko, Wu, Xianglin, Chen, Junjie
Format:	Artigo
Langue:	Inglês
Publié:	Taylor & Francis 2002
Sujets:	DNA Dynamics and Chromosome Structure
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC139754/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11756551/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.22.2.555-566.2002
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