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IL-6-mediated induction of MMP-9 is modulated by JAK-dependent IL-10 expression in macrophages()
The mechanisms by which IL-6 contributes to the pathogenesis of chronic inflammatory diseases and cancer are not fully understood. We previously reported that cyclooxygenase-2 (Cox-2)-dependent PGE(2) synthesis regulates macrophage matrix metalloproteinase (MMP)-9 expression, an endopeptidase that p...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3872272/ https://ncbi.nlm.nih.gov/pubmed/24285838 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1301906 |
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