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Number of Mutations Within CTL-Defined Epitopes of the Hepatitis B Virus (HBV) Core Region is Associated With HBV Disease Progression

The virologic determinants of progressive liver disease associated with hepatitis B virus (HBV) remain unclear. Previous investigations have associated HBV disease with specific mutations but this association may be confounded by HBV genotype, HLA haplotype of the infected individual or both. The as...

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Detalhes bibliográficos
Main Authors: Kim, Daniel, Lyoo, Kwang Soo, Smith, Davey, Hur, Wonhee, Hong, Sung Woo, Sung, Pil Soo, Yoon, Seung Kew, Mehta, Sanjay
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3872118/
https://ncbi.nlm.nih.gov/pubmed/22012714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jmv.22226
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