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Therapeutic polypeptides based on HBV core 18-27 epitope can induce CD(8)(+) CTL-mediated cytotoxicity in HLA-A2(+) human PBMCs
AIM: To explore how to improve the immunogenicity of HBcAg CTL epitope based polypeptides and to trigger an HBV-specific HLA I-restricted CD(8)(+) T cell response in vitro. METHODS: A new panel of mimetic therapeutic peptides based on the immunodominant B cell epitope of HBV PreS2 18-24 region, the...
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| Publicado no: | World J Gastroenterol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Baishideng Publishing Group Inc
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4572227/ https://ncbi.nlm.nih.gov/pubmed/15222033 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v10.i13.1902 |
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