Neutralization of Plasmodium falciparum merozoites by antibodies against PfRH5

There is intense interest in induction and characterization of strain-transcending neutralizing antibody against antigenically variable human pathogens. We have recently identified the human malaria parasite Plasmodium falciparum reticulocyte-binding protein homologue 5 (PfRH5) as a target of broadl...

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Bibliographic Details
Main Authors: Douglas, Alexander D., Williams, Andrew R., Knuepfer, Ellen, Illingworth, Joseph J., Furze, Julie M., Crosnier, Cécile, Choudhary, Prateek, Bustamante, Leyla Y., Zakutansky, Sara E., Awuah, Dennis K., Alanine, Daniel G. W., Theron, Michel, Worth, Andrew, Shimkets, Richard, Rayner, Julian C., Holder, Anthony A., Wright, Gavin J., Draper, Simon J.
Format: Artigo
Language:Inglês
Published: 2013
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3872115/
https://ncbi.nlm.nih.gov/pubmed/24293631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1302045
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