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Molecular Mechanisms of Hepatocellular Apoptosis Induced by Trovafloxacin-Tumor Necrosis Factor-alpha Interaction

Idiosyncratic drug-induced liver injury (IDILI) continues to be a significant human health problem. IDILI is characterized as occurring in a minority of individuals exposed to a drug, yet it accounts for as much as 17% of all cases of acute liver failure. Despite these concerns, the mechanisms under...

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書誌詳細
主要な著者: Beggs, Kevin M., Fullerton, Aaron M., Miyakawa, Kazuhisa, Ganey, Patricia E., Roth, Robert A.
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3871929/
https://ncbi.nlm.nih.gov/pubmed/24097668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kft226
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