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Evidence for reactive oxygen species inducing mutations in mammalian cells.

We have studied the mutagenicity (by selecting for mutants resistant to 6-thioguanine) and cytotoxicity (by determining cellular cloning efficiency) of physical and chemical agents in Chinese hamster ovary (CHO) cells, clone CHO-K1-BH4 (K1-BH4), and its radiation-hypersensitive transformant, AS52. A...

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Podrobná bibliografie
Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Hsie, A W, Recio, L, Katz, D S, Lee, C Q, Wagner, M, Schenley, R L
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 1986
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC387191/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2432598/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.24.9616
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