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Mutagenicity of arsenic in mammalian cells: Role of reactive oxygen species

Arsenite, the trivalent form of arsenic present in the environment, is a known human carcinogen that lacked mutagenic activity in bacterial and standard mammalian cell mutation assays. We show herein that when evaluated in an assay (A(L) cell assay), in which both intragenic and multilocus mutations...

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Detalhes bibliográficos
Main Authors: Hei, Tom K., Liu, Su X., Waldren, Charles
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC20936/
https://ncbi.nlm.nih.gov/pubmed/9653147
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