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Mutagenicity of arsenic in mammalian cells: Role of reactive oxygen species

Arsenite, the trivalent form of arsenic present in the environment, is a known human carcinogen that lacked mutagenic activity in bacterial and standard mammalian cell mutation assays. We show herein that when evaluated in an assay (A(L) cell assay), in which both intragenic and multilocus mutations...

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Détails bibliographiques
Auteurs principaux: Hei, Tom K., Liu, Su X., Waldren, Charles
Format: Artigo
Langue:Inglês
Publié: The National Academy of Sciences 1998
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC20936/
https://ncbi.nlm.nih.gov/pubmed/9653147
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