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Induction of oxyradicals by arsenic: Implication for mechanism of genotoxicity

Although arsenic is a well-established human carcinogen, the mechanisms by which it induces cancer remain poorly understood. We previously showed arsenite to be a potent mutagen in human–hamster hybrid (A(L)) cells, and that it induces predominantly multilocus deletions. We show here by confocal sca...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Liu, Su X., Athar, Mohammad, Lippai, Istvan, Waldren, Charles, Hei, Tom K.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC29310/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11172004/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.031482998
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