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Evidence for reactive oxygen species inducing mutations in mammalian cells.

We have studied the mutagenicity (by selecting for mutants resistant to 6-thioguanine) and cytotoxicity (by determining cellular cloning efficiency) of physical and chemical agents in Chinese hamster ovary (CHO) cells, clone CHO-K1-BH4 (K1-BH4), and its radiation-hypersensitive transformant, AS52. A...

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Detalhes bibliográficos
Main Authors: Hsie, A W, Recio, L, Katz, D S, Lee, C Q, Wagner, M, Schenley, R L
Formato: Artigo
Idioma:Inglês
Publicado em: 1986
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC387191/
https://ncbi.nlm.nih.gov/pubmed/2432598
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