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Identification of an activated c-Ki-ras oncogene in rat liver tumors induced by aflatoxin B1.
Weanling male Fischer rats were administered 40 intraperitoneal injections of aflatoxin B1 (25 micrograms per animal per day) over a 2-month period. This chronic dosing regimen resulted in the sequential formation of hyperplastic foci, preneoplastic nodules, and hepatocellular carcinomas in all of t...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
1986
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC387149/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3099282/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.24.9418 |
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