Identification of an activated c-Ki-ras oncogene in rat liver tumors induced by aflatoxin B1.

Weanling male Fischer rats were administered 40 intraperitoneal injections of aflatoxin B1 (25 micrograms per animal per day) over a 2-month period. This chronic dosing regimen resulted in the sequential formation of hyperplastic foci, preneoplastic nodules, and hepatocellular carcinomas in all of t...

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Bibliographic Details

Published in:	Proc Natl Acad Sci U S A
Main Authors:	McMahon, G, Hanson, L, Lee, J J, Wogan, G N
Format:	Artigo
Language:	Inglês
Published:	National Academy of Sciences 1986
Subjects:	Research Article
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC387149/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3099282/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.24.9418
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