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The N terminus of SKAP55 enables T cell adhesion to TCR and integrin ligands via distinct mechanisms
The T cell receptor (TCR) triggers the assembly of “SLP-76 microclusters,” which mediate signals required for T cell activation. In addition to regulating integrin activation, we show that Src kinase–associated phosphoprotein of 55 kD (SKAP55) is required for microcluster persistence and movement, j...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3871428/ https://ncbi.nlm.nih.gov/pubmed/24368808 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201305088 |
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