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Cell-Cycle Control of Developmentally Regulated Transcription Factors Accounts for Heterogeneity in Human Pluripotent Cells

Heterogeneity within pluripotent stem cell (PSC) populations is indicative of dynamic changes that occur when cells drift between different states. Although the role of metastability in PSCs is unclear, it appears to reflect heterogeneity in cell signaling. Using the Fucci cell-cycle indicator syste...

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Detalhes bibliográficos
Main Authors: Singh, Amar M., Chappell, James, Trost, Robert, Lin, Li, Wang, Tao, Tang, Jie, Wu, Hao, Zhao, Shaying, Jin, Peng, Dalton, Stephen
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3871385/
https://ncbi.nlm.nih.gov/pubmed/24371808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2013.10.009
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