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Cell-Cycle Control of Developmentally Regulated Transcription Factors Accounts for Heterogeneity in Human Pluripotent Cells

Heterogeneity within pluripotent stem cell (PSC) populations is indicative of dynamic changes that occur when cells drift between different states. Although the role of metastability in PSCs is unclear, it appears to reflect heterogeneity in cell signaling. Using the Fucci cell-cycle indicator syste...

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Main Authors: Singh, Amar M., Chappell, James, Trost, Robert, Lin, Li, Wang, Tao, Tang, Jie, Wu, Hao, Zhao, Shaying, Jin, Peng, Dalton, Stephen
格式: Artigo
語言:Inglês
出版: Elsevier 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3871385/
https://ncbi.nlm.nih.gov/pubmed/24371808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2013.10.009
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