Complement factor H–related hybrid protein deregulates complement in dense deposit disease

The renal disorder C3 glomerulopathy with dense deposit disease (C3G-DDD) pattern results from complement dysfunction and primarily affects children and young adults. There is no effective treatment, and patients often progress to end-stage renal failure. A small fraction of C3G-DDD cases linked to...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Chen, Qian, Wiesener, Michael, Eberhardt, Hannes U., Hartmann, Andrea, Uzonyi, Barbara, Kirschfink, Michael, Amann, Kerstin, Buettner, Maike, Goodship, Tim, Hugo, Christian, Skerka, Christine, Zipfel, Peter F.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Clinical Investigation 2013
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3871254/
https://ncbi.nlm.nih.gov/pubmed/24334459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI71866
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