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Allelic Variants of Complement Genes Associated with Dense Deposit Disease

The alternative pathway of the complement cascade plays a role in the pathogenesis of dense deposit disease (DDD). Deficiency of complement factor H and mutations in CFH associate with the development of DDD, but it is unknown whether allelic variants in other complement genes also associate with th...

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Autores principales: Abrera-Abeleda, Maria Asuncion, Nishimura, Carla, Frees, Kathy, Jones, Michael, Maga, Tara, Katz, Louis M., Zhang, Yuzhou, Smith, Richard J.H.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society of Nephrology 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3148710/
https://ncbi.nlm.nih.gov/pubmed/21784901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2010080795
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