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Aptamer-targeted inhibition of mTOR in T cells enhances antitumor immunity
Recent studies have underscored the importance of memory T cells in mediating protective immunity against pathogens and cancer. Pharmacological inhibition of regulators that mediate T cell differentiation promotes the differentiation of activated CD8(+) T cells into memory cells. Nonetheless, pharma...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Clinical Investigation
2013
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3871234/ https://ncbi.nlm.nih.gov/pubmed/24292708 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI69856 |
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