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Aptamer-targeted inhibition of mTOR in T cells enhances antitumor immunity

Recent studies have underscored the importance of memory T cells in mediating protective immunity against pathogens and cancer. Pharmacological inhibition of regulators that mediate T cell differentiation promotes the differentiation of activated CD8(+) T cells into memory cells. Nonetheless, pharma...

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Podrobná bibliografie
Hlavní autoři: Berezhnoy, Alexey, Castro, Iris, Levay, Agata, Malek, Thomas R., Gilboa, Eli
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3871234/
https://ncbi.nlm.nih.gov/pubmed/24292708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI69856
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