Aptamer-Targeted Attenuation of IL-2 Signaling in CD8(+) T Cells Enhances Antitumor Immunity

Immune responses elicited against cancer using existing therapies such as vaccines or immune stimulatory antibodies are often not curative. One way to potentiate antitumor immunity is to enhance the long-term persistence of anti-tumor CD8(+) T cells. Studies have shown that the persistence of activa...

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Bibliografski detalji
Izdano u:Mol Ther
Glavni autori: Rajagopalan, Anugraha, Berezhnoy, Alexey, Schrand, Brett, Puplampu-Dove, Yvonne, Gilboa, Eli
Format: Artigo
Jezik:Inglês
Izdano: American Society of Gene & Cell Therapy 2017
Teme:
Original Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5363184/
https://ncbi.nlm.nih.gov/pubmed/28129128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2016.10.021
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