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Aptamer-Targeted Attenuation of IL-2 Signaling in CD8(+) T Cells Enhances Antitumor Immunity

Immune responses elicited against cancer using existing therapies such as vaccines or immune stimulatory antibodies are often not curative. One way to potentiate antitumor immunity is to enhance the long-term persistence of anti-tumor CD8(+) T cells. Studies have shown that the persistence of activa...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Mol Ther
Päätekijät: Rajagopalan, Anugraha, Berezhnoy, Alexey, Schrand, Brett, Puplampu-Dove, Yvonne, Gilboa, Eli
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society of Gene & Cell Therapy 2017
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5363184/
https://ncbi.nlm.nih.gov/pubmed/28129128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2016.10.021
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